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Molecular Foundations for Biotechnology (MFB)

Status: Archived

Archived funding opportunity

This document has been archived. See NSF 23-554 for the latest version.

Important information for proposers

All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements. Submitting a proposal prior to a specified deadline does not negate this requirement.

Partnerships to Transform Emerging Industries


This initiative calls for fundamentally new approaches in chemistry to drive new directions in biotechnology, an important Industry of the Future (IotF). Collaborative high risk/high reward projects are sought; the research must involve innovative chemistry.

A multi-year campaign is envisioned (contingent on availability of funding), targeting broad annual themes. This year’s solicitation calls for synergistic scientific partnerships grounded in the principles of synthetic, physical organic and molecular recognition chemistry creating novel chemical biology tools to drive innovations in biotechnology.  The focus is on the development and deployment of fundamentally new techniques to modify the structure, function and/or fate of proteins interacting with small molecules for important applications in biotechnology.

Program contacts

Tingyu Li
tli@nsf.gov (703) 292-4949 MPS/CHE
Herman O. Sintim
hsintim@nsf.gov (703) 292-7244 MPS/CHE
Kelsey D. Cook
kcook@nsf.gov (703) 292-7490 MPS/CHE

Awards made through this program

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Map of recent awards made through this program