a yellow and orange close-up view of a quantum chip

NSF Quantum Leap Challenge Institutes

The U.S. National Science Foundation Quantum Leap Challenge Institutes (NSF QLCI) are large-scale interdisciplinary research projects focused on advancing quantum information science, engineering and technology through collaboration, education and innovation.

The institutes generate breakthroughs on difficult problems related to quantum information science and technology, which use physical properties of the quantum-scale universe — like superposition and entanglement — for novel approaches and applications. These breakthroughs can enable new areas of scientific exploration and technologies that enhance human health, national security and economic competitiveness. The goals of the institutes are aligned with the "National Quantum Initiative Act," which called for a coordinated federal effort to accelerate quantum research and development for the economic and national security of the U.S.

As part of their mission to tackle daunting quantum-focused challenges, the institutes foster collaborative partnerships between academia, government and industry. They also provide specialized education, training and workforce development opportunities to broaden participation in quantum science and engineering among more U.S. institutions and communities.


The NSF Quantum Leap Challenge Institutes

NSF Quantum Leap Challenge Institute for Quantum Sensing for Biophysics and Bioengineering (NSF QuBBE)

Led by the University of Chicago, NSF QuBBE researchers are developing new quantum-based methods and technologies for applications in biology and biomedical research.

Their work includes creating biocompatible quantum sensors, establishing protocols for sensing and imaging within cells, precision detection of the boundaries of tumors, revealing the pathways that inflammation takes within living things, and enabling more precise and immediate measurements of a range of biological properties.

NSF Quantum Leap Challenge Institute for Robust Quantum Simulation (NSF RQS)

Led by the University of Maryland, NSF RQS researchers are pioneering new ways to build, use and validate quantum simulations for chemistry, nuclear and high energy physics, materials science, computer science and other areas.

Their work includes creating and deploying new methods to verify the correctness of quantum simulations too complex for classical methods. They are also exploring new techniques for quantum computing, including photonic qubit systems, error correction, and new algorithms and software for faster and more efficient computation.

NSF Quantum Leap Challenge Institute for Hybrid Quantum Architectures and Networks (NSF HQAN)

Led by the University of Illinois Urbana-Champaign, NSF HQAN researchers are laying the scientific groundwork for future modular quantum computers that can use the properties of different kinds of qubits to achieve enhanced performance.

They are working to invent components and protocols that can be brought together into a sort of quantum computer motherboard, including quantum networks and processors, interconnects that convert quantum states between components, and other innovations that can advance practical quantum computing.

Led by the University of Colorado Boulder, NSF Q-SEnSE researchers are exploring the phenomenon of entanglement for yielding precision measurements through new quantum sensors with ultracold atoms and exceptionally precise lasers at their core.

Their work includes developing next-generation atomic clocks with increased precision, using networks of entangled atoms for quantum sensors, and other challenges aimed at enabling the production of practical and functional quantum systems by industry.

NSF Quantum Leap Challenge Institute for Quantum Computation (NSF CIQC)

Led by UC Berkeley, NSF CIQC researchers are addressing multiple fundamental challenges of developing functional quantum computers with capabilities beyond those of classical supercomputers.

Their work includes scaling up prototypes that incorporate a broad range of techniques using neutral atoms, photonic chips and others, testing and proving capabilities of quantum computers using advanced mathematics, and creating new computing architectures involving trapped electrons, complex atoms and more.

A shiny metal vacuum chamber with red light emanating from inside.

Learn more about quantum information science

In the quantum world, the laws of physics become peculiar. Researchers are exploring how to control the behavior of these quantum systems to create next-generation technologies for imaging, sensing, computing, modeling and communication.