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Supports new managing organizations to catalyze distributed, community-driven development and growth of open-source ecosystems.

Supports integrative, cross-disciplinary research that explores the mechanistic and eco-evolutionary responses of organisms to climate change, aiming to improve predictions, develop solutions for mitigating impacts and support the bioeconomy.

Supports projects that promote, improve and disseminate responsible and ethical research practices in STEM fields, focusing on individual, organizational and cultural factors influencing ethical conduct across career stages and research environments.

Supports networks of scientists focused on integrating biological research discoveries with innovations in education to improve learning experiences for undergraduates.

Supports research into synthetic microbial communities, including how they form and evolve, how to use them to address biological questions and/or how to build them for biotechnology or bioengineering applications.

Supports large-scale interdisciplinary research projects focused on advancing quantum information science, engineering and technology through collaboration, education and innovation, as part of the National Quantum Initiative.

Supports transitioning teams from research that is multidisciplinary to research that transcends disciplinary boundaries with novel conceptual frameworks, theories and methods.

Supports interdisciplinary collaborations integrating research on behavioral and/or social processes in mathematical epidemiological models. The goal of this program is to minimize unintended outcomes of public health interventions in response to pandemics.

Supports diverse, collaborative teams that perform research, education and training on critical questions that span multiple disciplines within and beyond biology.

Supports integrative research that develops advanced mathematical theories and methods to address complex biological challenges, thereby enhancing our understanding of diverse biological systems and informing public health policy.

Supports opportunities for scientists and engineers at the associate professor rank (or equivalent) to substantively enhance and advance their research program through synergistic partnerships.

Supports partnerships between researchers and local communities to pilot innovative, research-based solutions that address climate resilience and equitable access to essential resources, focusing on scalable, real-world impacts.

Supports renewal awards for active Long-term Ecological Research sites.

Supports partnerships between researchers and conservation practitioners to integrate science, action and evaluation, addressing urgent biodiversity challenges and advancing evidence-based conservation in the U.S.

Supports the design and implementation of research infrastructure — including equipment, cyberinfrastructure, large-scale datasets and personnel — whose total project costs are under $20 million.

Supports the design and implementation of Quantum Science and Technology Demonstration projects as part of the National Quantum Virtual Laboratory program.

Supports systemic change projects to enhance gender equity and inclusion for STEM faculty.

In 2016, the National Science Foundation (NSF) unveiled a set of “Big Ideas,” 10 bold, long-term research and process ideas that identify areas for future investment at the frontiers of science and engineering (see https://www.nsf.gov/news/special_reports/big_ideas/index.jsp). The Big Ideas represent unique...

Supports institutions in EPSCoR jurisdictions by providing funding for graduate fellowships for new or continuing students who received the distinction of NSF Graduate Research Fellowship Program (GRFP) Honorable Mention within the last three years.

Supports large-scale, long-term projects that focus on creating new scientific paradigms, establishing new scientific disciplines and developing transformative technologies while engaging the full spectrum of diverse talent that society has to offer.

Supports research and education to overcome barriers and enable new manufacturing capabilities. Focuses on cybermanufacturing, eco-manufacturing and biomanufacturing.

Supports the design, implementation and evaluation of projects that leverage the work of professional societies to advance diversity, equity and inclusion in the biological sciences.

Supports research at public and private historically Black colleges and universities to strengthen research capacity and promote engagement with NSF.

Supports early-career faculty who have the potential to serve as academic role models in research and education and to lead advances in the mission of their department or organization.

Supports intensive research by undergraduate students in any NSF-funded area of research. REU Sites engage a cohort of students in research projects related to a theme. REU Supplements engage students in research related to a new or ongoing NSF research award.