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Cellular Processes

Status: Archived

Archived funding opportunity

This document has been archived. See PD 13-1114 and NSF 24-539 for the latest documents.

Important information for proposers

All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements. Submitting a proposal prior to a specified deadline does not negate this requirement.


The Cellular Systems Cluster, one of three thematic areas within the Division of Molecular and Cellular Biosciences, supports research, across all taxa, into the structure and organization of cells and the dynamics of cellular processes.  Cell Biology is at a juncture where powerful new techniques in microscopy and biophysics (including live cell imaging, and the ability to study molecular function and behavior in the cell at high resolution, down to the single molecule level) are advancing rapidly.  At the same time, modeling and computational approaches have developed to the point where they can, in concert with accurate and informative experimental datasets, generate predictive models that can be tested experimentally. The Cellular Systems cluster is interested not only in traditional areas of cell biology (such as the organization, function, and dynamics of membranes, organelles and other subcellular compartments, and intracellular and transmembrane signal transduction mechanisms and cell-cell signaling processes) but also in the development of quantitative, theory-driven approaches to cell biology that integrate experimental studies at the molecular genetic, biochemical, biophysical, transcriptomic and proteomic levels.  Network theory (e.g., as applied to signal transduction) and molecular dynamic modeling (e.g., as applied to the structure/function relationships of cellular structures) are also of particular interest. While proposals using approaches and model systems traditional in the field of cell biology are welcome, studies focused on novel, unique approaches and on non-traditional model organisms are encouraged.

Program Directors:

Richard Rodewald. Cellular organization, compartmentation, biogenesis of organelles and regulation.



Updates and announcements

Program contacts

Richard Rodewald
rrodewal@nsf.gov (703) 292-7140
Richard J. Cyr
Program Director
rcyr@nsf.gov (703) 292-7124 BIO/MCB
Shelley Sazer
Program Director
ssazer@nsf.gov (703) 292-2968

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