Abstract collage of science-related imagery

Chemical Measurement and Imaging (CMI)

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NSF 22-605

Important information for proposers

All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements. Submitting a proposal prior to a specified deadline does not negate this requirement.

Supports research focusing on chemically-relevant measurement science and chemical imaging.

Supports research focusing on chemically-relevant measurement science and chemical imaging.


The Chemical Measurement and Imaging (CMI) Program supports research focusing on chemically-relevant measurement science and chemical imaging. Projects may target development of innovative approaches and instruments likely to be of use to the chemistry community, and/or improved understanding of new and existing methods. Research areas include, but are not limited to, analytical separation science; electroanalytical chemistry; and spectrometry (including atomic, molecular, magnetic resonance, and mass spectrometry). Development of new chemical imaging and measurement tools that probe chemical properties and processes is supported. Innovations enabling the monitoring and imaging of chemical and electronic processes across a wide range of time and length scales are also relevant. New approaches to data analysis and interpretation (including cheminformatics) are encouraged. Proposals addressing established techniques must seek improved understanding and/or innovative approaches to substantially broaden applicability. Sensor-related proposals are expected to address new approaches to chemical sensing, with prospects for broad utility and significant enhancement of current capabilities. 

Proposals addressing development of new instrumentation that enables chemical measurements likely to be of wide interest and utility to the chemistry research community should include the words "Instrument Development:" at the beginning of the title, and include, in the Project Description, consideration of a development timeline, potential utility, and prospects for the extension of the technique to other uses or fields, should it prove viable.

The CMI Program is also interested in proposal submissions in the following topical areas: Industrial partnerships are encouraged through the Grant Opportunities for Academic Liaison with Industry (GOALI) mechanism as means of enhancing use by the greater community, but concepts nearing commercialization are better fits to Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) Programs.

Proposals integrating innovative computational approaches with CMI-relevant research, such as those enabling efficient and effective data acquisition and analysis, are encouraged and should be submitted to the CMI Program through the Computational and Data Science and Engineering (CDS&E) funding opportunity.

Through the Critical Aspects of Sustainability (CAS) program, the Division of Chemistry looks to support basic research aimed at improving the sustainability of resources for future generations while maintaining or improving current products within a global society. Examples of CAS-relevant studies appropriate for the CMI Program include, but are not limited to: measurement science innovations targeting capabilities (such as remote or field-portable measurements) needed for improved characterization of important atmospheric and environmental systems; and innovations in separations science, targeting reduced use of costly and/or toxic solvents.

Research topics that are not of interest to the CMI Program: The CMI Program does not encourage proposals addressing: the development of techniques for topological/morphological imaging; research based on known sensing mechanisms, such as probe synthesis or assembly of array-type devices; or engineering aspects of membrane separations, microfluidics, and/or "lab-on-a-chip" device design, technology, and application. Proposals for the design and synthesis of novel molecular probes for sensing or contrast agents may be more suitable for the CSDM-B Program. Proposals for optimizing and/or utilizing established methods for specific applications should be directed to programs focused on the application. Proposals addressing innovations with anticipated utility primarily in other communities (e.g., biology or materials) are also not encouraged. Proposals with large equipment requests (over $150,000) may be better suited to the Major Research Instrumentation (MRI) Program.

Proposals submitted to this program (including individual and collaborative proposals, GOALIs) must be submitted to the CHE Disciplinary Research Programs solicitation. 


·         RUI proposals must be submitted to the RUI Solicitation during the regular proposal submission window for this program.

·         Proposals submitted in response to another solicitation (CAREER) should follow the solicitation guidelines (e.g. CAREER)

·         Workshop, EAGER, RAPID or RAISE proposals must be discussed with a Program Officer before submission, and then should only be submitted as instructed.

PIs are encouraged to monitor current funding priorities identified by the Foundation and the Executive and Legislative branches, and to highlight relevant synergies in their Project Summaries and Project Descriptions.

CHE is also committed to the inclusion of all people and institutions across all geographies in the U.S. because all are vital to the nation’s health, security and global leadership in STEM. NSF welcomes the submission of proposals to this funding opportunity that include the participation of the full spectrum of diverse talent in STEM, e.g., as PI, co-PI, senior personnel, postdoctoral scholars, graduate or undergraduate students or trainees. CHE also recognizes that STEM research and education occur at a wide range of institutions, including Minority-serving Institutions (MSIs), Primarily Undergraduate Institutions (PUIs), and two-year colleges, as well as major research institutions. CHE welcomes single institution and multi-institutional collaborative proposals from all types of institutions and encourages authentic and substantive collaborations and partnerships across diverse geographies and types of institutions. Proposals from EPSCoR jurisdictions are especially encouraged.

CHE occasionally supports forward-looking workshops attempting to inform roadmaps (included in the resulting workshop reports) for future research needs and directions relevant to chemical science. We are not generally able to support research symposia, including those at either special or recurring meetings and conferences.

For recent awards made by the program, search NSF award database with the Program Element Code 688000.

Program contacts

Administrative Program Support: Stephanie Smith, stesmith@nsf.gov or (703)292-7867

Kelsey D. Cook
kcook@nsf.gov (703) 292-7490 MPS/CHE
Jose Almirall
jalmiral@nsf.gov (703) 292-8840 MPS/CHE

Awards made through this program

Browse projects funded by this program
Map of recent awards made through this program