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Mathematical Foundations of Artificial Intelligence (MFAI)

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NSF 24-569

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NSF Financial Assistance awards (grants and cooperative agreements) made on or after October 1, 2024, will be subject to the applicable set of award conditions, dated October 1, 2024, available on the NSF website. These terms and conditions are consistent with the revised guidance specified in the OMB Guidance for Federal Financial Assistance published in the Federal Register on April 22, 2024.

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Supports research collaborations between mathematicians, statisticians, computer scientists, engineers and social behavior scientists to establish innovative and principled design and analysis approaches for AI technology.

Supports research collaborations between mathematicians, statisticians, computer scientists, engineers and social behavior scientists to establish innovative and principled design and analysis approaches for AI technology.

Synopsis

Machine Learning and Artificial Intelligence (AI) are enabling extraordinary scientific breakthroughs in fields ranging from protein folding, natural language processing, drug synthesis, and recommender systems to the discovery of novel engineering materials and products. These achievements lie at the confluence of mathematics, statistics, engineering and computer science, yet a clear explanation of the remarkable power and also the limitations of such AI systems has eluded scientists from all disciplines. Critical foundational gaps remain that, if not properly addressed, will soon limit advances in machine learning, curbing progress in artificial intelligence. It appears increasingly unlikely that these critical gaps can be surmounted with increased computational power and experimentation alone. Deeper mathematical understanding is essential to ensuring that AI can be harnessed to meet the future needs of society and enable broad scientific discovery, while forestalling the unintended consequences of a disruptive technology.  

The National Science Foundation Directorates for Mathematical and Physical Sciences (MPS), Computer and Information Science and Engineering (CISE), Engineering (ENG), and Social, Behavioral and Economic Sciences (SBE) will jointly sponsor research collaborations consisting of mathematicians, statisticians, computer scientists, engineers, and social and behavioral scientists focused on the mathematical and theoretical foundations of AI. Research activities should focus on the most challenging mathematical and theoretical questions aimed at understanding the capabilities, limitations, and emerging properties of AI methods as well as the development of novel, and mathematically grounded, design and analysis principles for the current and next generation of AI approaches.

Specific research goals include: establishing a fundamental mathematical understanding of the factors determining the capabilities and limitations of current and emerging generations of AI systems, including, but not limited to, foundation models, generative models, deep learning, statistical learning, federated learning, and other evolving paradigms; the development of mathematically grounded design and analysis principles for the current and next generations of AI systems; rigorous approaches for characterizing and validating machine learning algorithms and their predictions; research enabling provably reliable, translational, general-purpose AI systems and algorithms; encouragement of new collaborations across this interdisciplinary research community and from diverse institutions.

The overall goal is to establish innovative and principled design and analysis approaches for AI technology using creative yet theoretically grounded mathematical and statistical frameworks, yielding explainable and interpretable models that can enable sustainable, socially responsible, and trustworthy AI.  

 

Program contacts

Name Email Phone Organization
Stacey Levine
Program Director
mfai@nsf.gov (703) 292-2948 MPS/DMS
Eyad Abed
Program Director
mfai@nsf.gov (703) 292-2303 ENG/ECCS
Yulia Gel
Program Director
mfai@nsf.gov (703) 292-7888 MPS/DMS
Alfred Hero
Program Director
mfai@nsf.gov (703) 292-8910 CISE/CCF
Anthony Kuh
Program Director
mfai@nsf.gov (703) 292-4714 ENG/ECCS
Tracy J. Kimbrel
mfai@nsf.gov (703) 292-8910 CISE/CCF
Phillip A. Regalia
Program Director
mfai@nsf.gov (703) 292-2981 CISE/CCF
Christopher W. Stark
Program Director
mfai@nsf.gov (703) 292-4869
Reha M. Uzsoy
Program Director
mfai@nsf.gov (703) 292-2681 ENG/CMMI
Juan P. Wachs
Program Director
mfai@nsf.gov (703) 292-8714
Kenneth C. Whang
Program Director
mfai@nsf.gov (703) 292-5149 CISE/IIS
Joseph M. Whitmeyer
Program Director
mfai@nsf.gov (703) 292-7808 SBE/SES

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