Quantitative Systems Biotechnology (QSB)

As a result of recent advances in genomic and biochemical analysis, informatics, mathematics, and the engineering disciplines, it is now possible to approach an understanding of the integrated processes which translate the information contained in the genome into functioning biological entities.  Systems engineering approaches will be essential for characterizing the emergence of biological phenotypes from underlying hierarchies of interactions and environmental influences.  Understanding the quantitative systems behavior of cellular systems is important in its own right as well as providing a conceptual basis for biotechnological process development.

This Quantitative Systems Biotechnology solicitation seeks innovative high-risk/high-return proposals, which combine in-depth analysis of large-scale cellular biological systems, or their representations, with creative software tools for the development of computer models as well as complementary quantitative experimental approaches.  Multidisciplinary proposals are encouraged.